P‐14 Use of lufenuron in the therapy of canine and feline dermatophytosis in São Paulo (Brazil)
Identifieur interne : 008A56 ( Main/Exploration ); précédent : 008A55; suivant : 008A57P‐14 Use of lufenuron in the therapy of canine and feline dermatophytosis in São Paulo (Brazil)
Auteurs : M. Sonoda [Brésil] ; A. C. Balda [Brésil] ; M. Otsuka [Brésil] ; W. Gambale [Brésil] ; C. E. Larsson [Brésil]Source :
- Veterinary Dermatology [ 0959-4493 ] ; 2004-08.
Abstract
The goal of this study was to evaluate the efficacy of lufenuron in the treatment of animals with dermatophytosis [M. canis or M. gypseum (n = 48) and T. rubrum (n = 1)]. The study was performed over a 2‐year period. The 49 animals (23 dogs and 26 cats) were randomly separated into four groups, each one receiving 50–120 mg/kg of lufenuron, divided into one to four doses administered at various intervals. Liver enzyme measurement were performed on all animals. The results showed clinical and mycological cure in 22–60% of the animals treated in the study, with the highest efficacy in the group treated with 120 mg/kg given in two doses at a 3‐week interval (group IV). No systemic or cutaneous side effects or changes in liver enzyme levels were observed in any of the animals. Persian cats and Yorkshire terrier dogs had the highest rates of therapy failure. Lufenuron was more effective in dogs than cats. Morphological changes occurred in isolated Microsporum spp. colonies on culture. Funding: Self‐funded.
Url:
DOI: 10.1111/j.1365-3164.2004.00414_14.x
Affiliations:
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Use of lufenuron in the therapy of canine and feline dermatophytosis in São Paulo (Brazil)</title><author><name sortKey="Sonoda, M" sort="Sonoda, M" uniqKey="Sonoda M" first="M." last="Sonoda">M. Sonoda</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Balda, A C" sort="Balda, A C" uniqKey="Balda A" first="A. C." last="Balda">A. C. 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Otsuka</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Gambale, W" sort="Gambale, W" uniqKey="Gambale W" first="W." last="Gambale">W. Gambale</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Larsson, C E" sort="Larsson, C E" uniqKey="Larsson C" first="C. E." last="Larsson">C. E. Larsson</name><affiliation wicri:level="4"><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculdade de Medicina Veterinária, Universidade de São Paulo, São Paulo, Brazil; Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Veterinary Dermatology</title><title level="j" type="alt">VETERINARY DERMATOLOGY</title><idno type="ISSN">0959-4493</idno><idno type="eISSN">1365-3164</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="page" from="45">45</biblScope><biblScope unit="page" to="45">45</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-08">2004-08</date></imprint><idno type="ISSN">0959-4493</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0959-4493</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The goal of this study was to evaluate the efficacy of lufenuron in the treatment of animals with dermatophytosis [M. canis or M. gypseum (n = 48) and T. rubrum (n = 1)]. The study was performed over a 2‐year period. The 49 animals (23 dogs and 26 cats) were randomly separated into four groups, each one receiving 50–120 mg/kg of lufenuron, divided into one to four doses administered at various intervals. Liver enzyme measurement were performed on all animals. The results showed clinical and mycological cure in 22–60% of the animals treated in the study, with the highest efficacy in the group treated with 120 mg/kg given in two doses at a 3‐week interval (group IV). No systemic or cutaneous side effects or changes in liver enzyme levels were observed in any of the animals. Persian cats and Yorkshire terrier dogs had the highest rates of therapy failure. Lufenuron was more effective in dogs than cats. Morphological changes occurred in isolated Microsporum spp. colonies on culture. Funding: Self‐funded.</div></front></TEI><affiliations><list><country><li>Brésil</li></country><region><li>État de São Paulo</li></region><settlement><li>São Paulo</li></settlement><orgName><li>Université de São Paulo</li></orgName></list><tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="Sonoda, M" sort="Sonoda, M" uniqKey="Sonoda M" first="M." last="Sonoda">M. Sonoda</name></region><name sortKey="Balda, A C" sort="Balda, A C" uniqKey="Balda A" first="A. C." last="Balda">A. C. Balda</name><name sortKey="Gambale, W" sort="Gambale, W" uniqKey="Gambale W" first="W." last="Gambale">W. Gambale</name><name sortKey="Larsson, C E" sort="Larsson, C E" uniqKey="Larsson C" first="C. E." last="Larsson">C. E. Larsson</name><name sortKey="Otsuka, M" sort="Otsuka, M" uniqKey="Otsuka M" first="M." last="Otsuka">M. Otsuka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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